Microbial Characteristics Associated with Different Clinical Phenotypes of Inflammatory Bowel Disease

Inflammatory bowel disease (IBD) is a chronic debilitating condition that manifests with diverse clinical phenotypes. Patients with different IBD phenotypes often respond differently to treatment, leading to varying prognoses. Given the critical role of the gut microbiome in the pathogenesis and progression of IBD, this study aims to investigate the microbial composition and functional differences across IBD patients with different clinical phenotypes. By integrating clinical phenotype data with fecal microbial, fecal metabolomics, and blood metabolomic datasets, this project seeks to establish a foundation for stratified and precision diagnosis and treatment of IBD.